b'ABSTR ACT / BIOGR APHY15 Se-Jin Lee, M.D., Ph.D.Professor, The Jackson Laboratory; Presidential Distinguished Professor; University of Connecticut School of MedicineMyostatin: A Molecular Rheostat for Muscle MassDr. Lee will discuss his work on the control of muscle growth by myostatin and a recent study in which he investigated the effect of targeting the myostatin signaling pathway in mice that were sent to the International Space Station.Dr. Se-Jin Lee obtained his Bachelors degree from Harvard College in 1981, graduating summa cum laude in Biochemical Sciences. He then entered the Medical Scientist Training Program at Johns Hopkins University School of Medicine, where he pursued his graduate studies with Dr. Daniel Nathans in the Department of Molecular Biology and Genetics. After obtaining his M.D. and Ph.D. degrees in 1989, Dr. Lee joined the Carnegie Institution of Washingtons Department of Embryology as a Staff Associate, where he initiated his studies investigating the role of secreted proteins in regulating embryonic development and adult tissue homeostasis. Dr. Lee returned to the Department of Molecular Biology and Genetics at Johns Hopkins as a faculty member in 1991 and achieved the rank of Professor in 2001. In 2013, Dr. Lee was named as the inaugural recipient of the Michael and Ann Hankin and Partners of Brown Advisory Professorship in Scientific Innovation. In 2017, Dr. Lee moved his research program to Connecticut, where he holds a joint appointment as Presidential Distinguished Professor at University of Connecticut and Professor at The Jackson Laboratory. Dr. Lee is best known for his discovery of myostatin as a master regulator of skeletal muscle mass. In recognition of this work, Dr. Lee was elected to the U.S. National Academy of Sciences in 2012 and was awarded the Rolf Luft Award and the Ho-Am Prize in Medicine in 2013. Dr. Lee was elected as Fellow of the National Academy of Inventors in 2015.'